If it was freezing temps outside, I would keep the thermostat set low during the day if gone, as it would help keep condensation down. Ours is never about 9°C (48°F) anyway, unless we bump it a bit for changing, or should we be sitting inside.
If gone for multi days, I would just shut it down for that time.
2017 Escape 5.0 TA (someday soon, I hope
2015 Ford F150 Lariat 3.5L EcoBoost
2009 Escape 19 (previous)
“Most folks are about as happy as they make up their minds to be.” — Abraham Lincoln