I have a 19 Escape and not sure if the tank is 20 Imperial or US gallons. According to my math 20 Imperial gallons is more volume at 91 litres versus 76 litres for 20 US gallons. I error on side of caution so I add 455 mLs of bleach (2 cups) (5 mLs/L x 91 L = 455 mLs) to a container of water and pour into the water tank.
I fill the water tank full, let it slosh around a bit but moving around in the trailer for 10 minutes or so, then run it through all the water lines with the water pump on (sink, bathroom sink and shower, and outside shower. Let it sit in the water lines for a few minutes, drain the water tank, fill tank with fresh water, run through the water lines again, then repeat one more time.
It takes a bit of time but I like knowing the system is clean. We use the water tank to cook and drink from.