We drove most of that route last February. We stayed on I-5 through N. California and then cut over to Reno from there. We stayed on the route you show until we turned off to Las Vegas where we had a RV camp reservation. I think you will find it is a great route to drive. Some traffic, but not crowded and sometimes you won't see other cars at all. A lot of straight sections of the highway with long sight views. My only concern would be to check for snowfall. This highway won't get cleared as fast as say I-5.
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